BDBM50153842 CHEMBL188122::N-[5-(3-Dimethylamino-benzoylamino)-2-fluoro-phenyl]-3,4-dimethoxy-benzamide

SMILES: COc1ccc(cc1OC)C(=O)Nc1cc(NC(=O)c2cccc(c2)N(C)C)ccc1F

InChI Key: InChIKey=PCDGNWQNRNLJIJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50153842 (CHEMBL188122 | N-[5-(3-Dimethylamino-benzoylamino)...) Show SMILES COc1ccc(cc1OC)C(=O)Nc1cc(NC(=O)c2cccc(c2)N(C)C)ccc1F Show InChI InChI=1S/C24H24FN3O4/c1-28(2)18-7-5-6-15(12-18)23(29)26-17-9-10-19(25)20(14-17)27-24(30)16-8-11-21(31-3)22(13-16)32-4/h5-14H,1-4H3,(H,26,29)(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Concentration required to inhibit human mitogen activated protein kinase p38 activity				Bioorg Med Chem Lett 14: 5383-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.006 BindingDB Entry DOI: 10.7270/Q28G8K57
					More data for this Ligand-Target Pair