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SMILES: Cc1ccc(NC(=O)c2cc(F)cc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2ccccn2)cc1

InChI Key: InChIKey=ZAWXZFUSGKYODR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153843   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50153843
PNG
(3-Fluoro-N-{4-methyl-3-[4-(pyridin-2-ylmethoxy)-be...)
Show SMILES Cc1ccc(NC(=O)c2cc(F)cc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2ccccn2)cc1
Show InChI InChI=1S/C31H29FN4O4/c1-21-5-8-25(34-31(38)23-16-24(32)18-27(17-23)36-12-14-39-15-13-36)19-29(21)35-30(37)22-6-9-28(10-7-22)40-20-26-4-2-3-11-33-26/h2-11,16-19H,12-15,20H2,1H3,(H,34,38)(H,35,37)
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AstraZeneca

Curated by ChEMBL


Assay Description
Concentration required to inhibit human mitogen activated protein kinase p38 activity

Bioorg Med Chem Lett 14: 5383-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.006
BindingDB Entry DOI: 10.7270/Q28G8K57
More data for this
Ligand-Target Pair