BindingDB logo
myBDB logout

null

SMILES: Cc1nc(COc2ccc(cc2)C(=O)Nc2cc(NC(=O)c3cccc(c3)N3CCOCC3)ccc2C)cs1

InChI Key: InChIKey=YPRJRFRMPMLFEL-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153845   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50153845
PNG
(4-methyl-3-[4-(2-methyl-1,3-thiazol-4-ylmethoxy)ph...)
Show SMILES Cc1nc(COc2ccc(cc2)C(=O)Nc2cc(NC(=O)c3cccc(c3)N3CCOCC3)ccc2C)cs1
Show InChI InChI=1S/C30H30N4O4S/c1-20-6-9-24(32-30(36)23-4-3-5-26(16-23)34-12-14-37-15-13-34)17-28(20)33-29(35)22-7-10-27(11-8-22)38-18-25-19-39-21(2)31-25/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,32,36)(H,33,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Concentration required to inhibit human mitogen activated protein kinase p38 activity

Bioorg Med Chem Lett 14: 5383-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.006
BindingDB Entry DOI: 10.7270/Q28G8K57
More data for this
Ligand-Target Pair