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BDBM50153935 1,1-Bis-(4-fluoro-phenyl)-3-[4-(4-methanesulfonyl-benzyl)-[1,4]diazepan-1-yl]-propan-1-ol::CHEMBL187701

SMILES: CS(=O)(=O)c1ccc(CN2CCCN(CCC(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1

InChI Key: InChIKey=MXBVGHFRPXPRKM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153935   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50153935
PNG
(1,1-Bis-(4-fluoro-phenyl)-3-[4-(4-methanesulfonyl-...)
Show SMILES CS(=O)(=O)c1ccc(CN2CCCN(CCC(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1
Show InChI InChI=1S/C28H32F2N2O3S/c1-36(34,35)27-13-3-22(4-14-27)21-32-17-2-16-31(19-20-32)18-15-28(33,23-5-9-25(29)10-6-23)24-7-11-26(30)12-8-24/h3-14,33H,2,15-21H2,1H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Institute for Bio-medical Research

Curated by ChEMBL


Assay Description
Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cell

Bioorg Med Chem Lett 14: 5407-11 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.008
BindingDB Entry DOI: 10.7270/Q2125S4T
More data for this
Ligand-Target Pair