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SMILES: COc1c(Br)c(O)c(Br)c2nc(oc12)-c1ccc(O)c(F)c1

InChI Key: InChIKey=DPCGKGDOPBWHDL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50154046 (4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-methox...) Show SMILES COc1c(Br)c(O)c(Br)c2nc(oc12)-c1ccc(O)c(F)c1 Show InChI InChI=1S/C14H8Br2FNO4/c1-21-12-9(16)11(20)8(15)10-13(12)22-14(18-10)5-2-3-7(19)6(17)4-5/h2-4,19-20H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	559	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154046 (4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-methox...) Show SMILES COc1c(Br)c(O)c(Br)c2nc(oc12)-c1ccc(O)c(F)c1 Show InChI InChI=1S/C14H8Br2FNO4/c1-21-12-9(16)11(20)8(15)10-13(12)22-14(18-10)5-2-3-7(19)6(17)4-5/h2-4,19-20H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Yantai University Curated by ChEMBL					Assay Description Binding affinity to ERbeta (unknown origin)				Eur J Med Chem 43: 43-52 (2008) Article DOI: 10.1016/j.ejmech.2007.03.002 BindingDB Entry DOI: 10.7270/Q2WD40BT
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154046 (4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-methox...) Show SMILES COc1c(Br)c(O)c(Br)c2nc(oc12)-c1ccc(O)c(F)c1 Show InChI InChI=1S/C14H8Br2FNO4/c1-21-12-9(16)11(20)8(15)10-13(12)22-14(18-10)5-2-3-7(19)6(17)4-5/h2-4,19-20H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair