BDBM50154065 4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl-benzooxazol-5-ol::4,6-dibromo-2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol::CHEMBL182751

SMILES: Oc1ccc(cc1F)-c1nc2c(Br)c(O)c(Br)c(C=C)c2o1

InChI Key: InChIKey=BNIOVAWOIGCLML-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50154065 (4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl-...) Show SMILES Oc1ccc(cc1F)-c1nc2c(Br)c(O)c(Br)c(C=C)c2o1 Show InChI InChI=1S/C15H8Br2FNO3/c1-2-7-10(16)13(21)11(17)12-14(7)22-15(19-12)6-3-4-9(20)8(18)5-6/h2-5,20-21H,1H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	803	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154065 (4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl-...) Show SMILES Oc1ccc(cc1F)-c1nc2c(Br)c(O)c(Br)c(C=C)c2o1 Show InChI InChI=1S/C15H8Br2FNO3/c1-2-7-10(16)13(21)11(17)12-14(7)22-15(19-12)6-3-4-9(20)8(18)5-6/h2-5,20-21H,1H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Yantai University Curated by ChEMBL					Assay Description Binding affinity to ERbeta (unknown origin)				Eur J Med Chem 43: 43-52 (2008) Article DOI: 10.1016/j.ejmech.2007.03.002 BindingDB Entry DOI: 10.7270/Q2WD40BT
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154065 (4,6-Dibromo-2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl-...) Show SMILES Oc1ccc(cc1F)-c1nc2c(Br)c(O)c(Br)c(C=C)c2o1 Show InChI InChI=1S/C15H8Br2FNO3/c1-2-7-10(16)13(21)11(17)12-14(7)22-15(19-12)6-3-4-9(20)8(18)5-6/h2-5,20-21H,1H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair