BDBM50154132 2-(2,6-Difluoro-4-hydroxy-phenyl)-7-vinyl-benzooxazol-5-ol::CHEMBL188517

SMILES: Oc1cc(F)c(-c2nc3cc(O)cc(C=C)c3o2)c(F)c1

InChI Key: InChIKey=QQYOOMZAIWLSOT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50154132 (2-(2,6-Difluoro-4-hydroxy-phenyl)-7-vinyl-benzooxa...) Show SMILES Oc1cc(F)c(-c2nc3cc(O)cc(C=C)c3o2)c(F)c1 Show InChI InChI=1S/C15H9F2NO3/c1-2-7-3-8(19)6-12-14(7)21-15(18-12)13-10(16)4-9(20)5-11(13)17/h2-6,19-20H,1H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50154132 (2-(2,6-Difluoro-4-hydroxy-phenyl)-7-vinyl-benzooxa...) Show SMILES Oc1cc(F)c(-c2nc3cc(O)cc(C=C)c3o2)c(F)c1 Show InChI InChI=1S/C15H9F2NO3/c1-2-7-3-8(19)6-12-14(7)21-15(18-12)13-10(16)4-9(20)5-11(13)17/h2-6,19-20H,1H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	249	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair