null

SMILES: CNC(=O)COC(=O)[C@H](CCC(N)=O)NC(=S)Nc1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=OCIOZBZMYBMEGL-NSHDSACASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50154324 (4-Carbamoyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-...) Show SMILES CNC(=O)COC(=O)[C@H](CCC(N)=O)NC(=S)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O6S2/c1-18-13(22)8-26-14(23)11(6-7-12(16)21)20-15(27)19-9-2-4-10(5-3-9)28(17,24)25/h2-5,11H,6-8H2,1H3,(H2,16,21)(H,18,22)(H2,17,24,25)(H2,19,20,27)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibitory activity against human Carbonic anhydrase II				J Med Chem 47: 5224-9 (2004) Article DOI: 10.1021/jm049692i BindingDB Entry DOI: 10.7270/Q24F1RHJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50154324 (4-Carbamoyl-2-[3-(4-sulfamoyl-phenyl)-thioureido]-...) Show SMILES CNC(=O)COC(=O)[C@H](CCC(N)=O)NC(=S)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O6S2/c1-18-13(22)8-26-14(23)11(6-7-12(16)21)20-15(27)19-9-2-4-10(5-3-9)28(17,24)25/h2-5,11H,6-8H2,1H3,(H2,16,21)(H,18,22)(H2,17,24,25)(H2,19,20,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibitory activity against human Carbonic anhydrase I				J Med Chem 47: 5224-9 (2004) Article DOI: 10.1021/jm049692i BindingDB Entry DOI: 10.7270/Q24F1RHJ
					More data for this Ligand-Target Pair