BDBM50154521 CHEMBL3775532

SMILES: Fc1ccc(cc1F)-c1c[nH]c(n1)[C@H]1Cc2c([nH]c3ccccc23)[C@H](N1)C1CCOCC1

InChI Key: InChIKey=ZLYIXARJBBRFDR-FYYLOGMGSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50154521 (CHEMBL3775532) Show SMILES Fc1ccc(cc1F)-c1c[nH]c(n1)[C@H]1Cc2c([nH]c3ccccc23)[C@H](N1)C1CCOCC1 |r| Show InChI InChI=1S/C25H24F2N4O/c26-18-6-5-15(11-19(18)27)22-13-28-25(31-22)21-12-17-16-3-1-2-4-20(16)29-24(17)23(30-21)14-7-9-32-10-8-14/h1-6,11,13-14,21,23,29-30H,7-10,12H2,(H,28,31)/t21-,23-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 26: 1529-35 (2016) BindingDB Entry DOI: 10.7270/Q2ZG6V4J
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50154521 (CHEMBL3775532) Show SMILES Fc1ccc(cc1F)-c1c[nH]c(n1)[C@H]1Cc2c([nH]c3ccccc23)[C@H](N1)C1CCOCC1 |r| Show InChI InChI=1S/C25H24F2N4O/c26-18-6-5-15(11-19(18)27)22-13-28-25(31-22)21-12-17-16-3-1-2-4-20(16)29-24(17)23(30-21)14-7-9-32-10-8-14/h1-6,11,13-14,21,23,29-30H,7-10,12H2,(H,28,31)/t21-,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human somatostatin receptor type 3				Bioorg Med Chem Lett 26: 1529-35 (2016) BindingDB Entry DOI: 10.7270/Q2ZG6V4J
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50154521 (CHEMBL3775532) Show SMILES Fc1ccc(cc1F)-c1c[nH]c(n1)[C@H]1Cc2c([nH]c3ccccc23)[C@H](N1)C1CCOCC1 |r| Show InChI InChI=1S/C25H24F2N4O/c26-18-6-5-15(11-19(18)27)22-13-28-25(31-22)21-12-17-16-3-1-2-4-20(16)29-24(17)23(30-21)14-7-9-32-10-8-14/h1-6,11,13-14,21,23,29-30H,7-10,12H2,(H,28,31)/t21-,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human somatostatin receptor type 3 assessed as inhibition of cAMP levels				Bioorg Med Chem Lett 26: 1529-35 (2016) BindingDB Entry DOI: 10.7270/Q2ZG6V4J
					More data for this Ligand-Target Pair