null

SMILES: Cc1cc(cc(C)c1C)-c1c(OCCC2OCCO2)c2cc(C(=O)Nc3cnsn3)c(Cl)cc2[nH]c1=O

InChI Key: InChIKey=YHJHKRDSRZWAOT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50155352 (7-Chloro-4-(2-[1,3]dioxolan-2-yl-ethoxy)-2-oxo-3-(...) Show SMILES Cc1cc(cc(C)c1C)-c1c(OCCC2OCCO2)c2cc(C(=O)Nc3cnsn3)c(Cl)cc2[nH]c1=O Show InChI InChI=1S/C26H25ClN4O5S/c1-13-8-16(9-14(2)15(13)3)23-24(36-5-4-22-34-6-7-35-22)18-10-17(19(27)11-20(18)29-26(23)33)25(32)30-21-12-28-37-31-21/h8-12,22H,4-7H2,1-3H3,(H,29,33)(H,30,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin releasing hormone receptor expressed in CHO cells was determined by using [125I]-buserelin as radioligand				Bioorg Med Chem Lett 14: 5599-603 (2004) Article DOI: 10.1016/j.bmcl.2004.08.056 BindingDB Entry DOI: 10.7270/Q20V8C8D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50155352 (7-Chloro-4-(2-[1,3]dioxolan-2-yl-ethoxy)-2-oxo-3-(...) Show SMILES Cc1cc(cc(C)c1C)-c1c(OCCC2OCCO2)c2cc(C(=O)Nc3cnsn3)c(Cl)cc2[nH]c1=O Show InChI InChI=1S/C26H25ClN4O5S/c1-13-8-16(9-14(2)15(13)3)23-24(36-5-4-22-34-6-7-35-22)18-10-17(19(27)11-20(18)29-26(23)33)25(32)30-21-12-28-37-31-21/h8-12,22H,4-7H2,1-3H3,(H,29,33)(H,30,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells expressing GnRH receptor				Bioorg Med Chem Lett 14: 5599-603 (2004) Article DOI: 10.1016/j.bmcl.2004.08.056 BindingDB Entry DOI: 10.7270/Q20V8C8D
					More data for this Ligand-Target Pair