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SMILES: Clc1ccc(C[C@@H](NC(=O)C2CCNCC2)C(=O)N2CCN(CC2)c2ccccc2CNCCc2cccs2)cc1

InChI Key: InChIKey=UUPRARKOAAGHQH-GDLZYMKVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155401   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50155401
PNG
(CHEMBL363122 | Piperidine-4-carboxylic acid [(R)-1...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)C2CCNCC2)C(=O)N2CCN(CC2)c2ccccc2CNCCc2cccs2)cc1
Show InChI InChI=1S/C32H40ClN5O2S/c33-27-9-7-24(8-10-27)22-29(36-31(39)25-11-14-34-15-12-25)32(40)38-19-17-37(18-20-38)30-6-2-1-4-26(30)23-35-16-13-28-5-3-21-41-28/h1-10,21,25,29,34-35H,11-20,22-23H2,(H,36,39)/t29-/m1/s1
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Similars
Article
PubMed
 26n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Tested for inhibition of binding to MC4 receptor

Bioorg Med Chem Lett 14: 5605-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.055
BindingDB Entry DOI: 10.7270/Q2DB82K8
More data for this
Ligand-Target Pair