BDBM50155446 1,3,7-Trihydroxy xanthone (3)::1,3,7-Trihydroxy-xanthen-9-one::1,3,7-trihydroxy-9H-xanthen-9-one::CHEMBL361025

SMILES: Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1

InChI Key: InChIKey=JJUNZBRHHGLJQW-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50155446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	6.8	30
University of Peshawar					Assay Description Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffer containing 100 mM urea were incubated with 5 &...				J Enzyme Inhib Med Chem 25: 296-9 (2010) Article DOI: 10.3109/14756360903179385 BindingDB Entry DOI: 10.7270/Q2TB15TQ
					More data for this Ligand-Target Pair
Fatty acid synthase (Homo sapiens (Human))	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of FAS				Bioorg Med Chem Lett 20: 6045-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.061 BindingDB Entry DOI: 10.7270/Q2TT4R6N
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UNNE Curated by ChEMBL					Assay Description Concentration required to inhibit monoamine oxidase activity by 50%				Bioorg Med Chem Lett 14: 5611-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.066 BindingDB Entry DOI: 10.7270/Q2W37VS1
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of Influenza A virus H1N1 neuraminidase using 4-MU-NANA as substrate by fluorescence assay				Bioorg Med Chem Lett 22: 3688-92 (2012) Article DOI: 10.1016/j.bmcl.2012.04.028 BindingDB Entry DOI: 10.7270/Q27947JG
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant using 4-MU-NANA as substrate by fluorescence assay				Bioorg Med Chem Lett 22: 3688-92 (2012) Article DOI: 10.1016/j.bmcl.2012.04.028 BindingDB Entry DOI: 10.7270/Q27947JG
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of Influenza A virus H9N2 neuraminidase using 4-MU-NANA as substrate by fluorescence assay				Bioorg Med Chem Lett 22: 3688-92 (2012) Article DOI: 10.1016/j.bmcl.2012.04.028 BindingDB Entry DOI: 10.7270/Q27947JG
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50155446 (1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...) Show SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1 Show InChI InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of wild type H1N1 swine influenza virus neuraminidase using 4-MU-NANA as substrate by fluorescence assay				Bioorg Med Chem Lett 22: 3688-92 (2012) Article DOI: 10.1016/j.bmcl.2012.04.028 BindingDB Entry DOI: 10.7270/Q27947JG
					More data for this Ligand-Target Pair