BindingDB PrimarySearch

BDBM50155447 1,3,6,7-Tetrahydroxy-xanthen-9-one::1,3,6,7-tetrahydroxyxantone::CHEMBL187265

SMILES: Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O

InChI Key: InChIKey=ZHTQCPCDXKMMLU-UHFFFAOYSA-N

Data: 1 KI 6 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50155447
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE by Lineweaver-Burk plot				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
UNNE Curated by ChEMBL					Assay Description Concentration required to inhibit monoamine oxidase activity by 50%				Bioorg Med Chem Lett 14: 5611-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.066 BindingDB Entry DOI: 10.7270/Q2W37VS1
UNNE Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
7,8-dihydro-8-oxoguanine triphosphatase (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP ...				Eur J Med Chem 167: 153-160 (2019) Article DOI: 10.1016/j.ejmech.2019.02.011
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of bovine Xanthine oxidase assessed as reduction in uric acid level by spectrophotometry				Bioorg Med Chem Lett 21: 4013-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.140 BindingDB Entry DOI: 10.7270/Q2KW5GCG
Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1 catalytic domain incubated for 20 mins by fluorimetric assay				Bioorg Med Chem 20: 4164-71 (2012) Article DOI: 10.1016/j.bmc.2012.04.063 BindingDB Entry DOI: 10.7270/Q22808NT
					More data for this Ligand-Target Pair
Fatty acid synthase (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of FAS				Bioorg Med Chem Lett 20: 6045-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.061 BindingDB Entry DOI: 10.7270/Q2TT4R6N
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair