BDBM50155451 3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester::CHEMBL184123

SMILES: FCCCN1C2CCC1C(C(C2)c1ccc(Br)cc1)C(=O)OCCF

InChI Key: InChIKey=XXLBWUCJODELRH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50155451 (3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...) Show SMILES FCCCN1C2CCC1C(C(C2)c1ccc(Br)cc1)C(=O)OCCF |TLB:19:9:4:7.6,3:4:9.10.11:7.6,THB:12:10:4:7.6| Show InChI InChI=1S/C19H24BrF2NO2/c20-14-4-2-13(3-5-14)16-12-15-6-7-17(23(15)10-1-8-21)18(16)19(24)25-11-9-22/h2-5,15-18H,1,6-12H2	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.03	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]-nisoxetine from norepinephrine transporter of rat cerebral corticex homogenate				Bioorg Med Chem Lett 14: 5635-9 (2004) Article DOI: 10.1016/j.bmcl.2004.08.049 BindingDB Entry DOI: 10.7270/Q2RB743J
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50155451 (3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...) Show SMILES FCCCN1C2CCC1C(C(C2)c1ccc(Br)cc1)C(=O)OCCF |TLB:19:9:4:7.6,3:4:9.10.11:7.6,THB:12:10:4:7.6| Show InChI InChI=1S/C19H24BrF2NO2/c20-14-4-2-13(3-5-14)16-12-15-6-7-17(23(15)10-1-8-21)18(16)19(24)25-11-9-22/h2-5,15-18H,1,6-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]-CIT from dopamine transporter of rat striatal homogenate				Bioorg Med Chem Lett 14: 5635-9 (2004) Article DOI: 10.1016/j.bmcl.2004.08.049 BindingDB Entry DOI: 10.7270/Q2RB743J
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50155451 (3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...) Show SMILES FCCCN1C2CCC1C(C(C2)c1ccc(Br)cc1)C(=O)OCCF |TLB:19:9:4:7.6,3:4:9.10.11:7.6,THB:12:10:4:7.6| Show InChI InChI=1S/C19H24BrF2NO2/c20-14-4-2-13(3-5-14)16-12-15-6-7-17(23(15)10-1-8-21)18(16)19(24)25-11-9-22/h2-5,15-18H,1,6-12H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]-cyanoimiprimine from serotonin transporter of rat cerebral cortical homogenate				Bioorg Med Chem Lett 14: 5635-9 (2004) Article DOI: 10.1016/j.bmcl.2004.08.049 BindingDB Entry DOI: 10.7270/Q2RB743J
					More data for this Ligand-Target Pair