BDBM50155487 CHEMBL185900::{(E)-5-[4-Hydroxy-5-((2E,4E)-2-methyl-nona-2,4-dienoyl)-6-oxo-6H-pyran-2-yl]-hex-1-enyl}-carbamic acid methyl ester

SMILES: CCCCC=CC=C(C)C(=O)c1c(O)cc(oc1=O)C(C)CCCC=NC(=O)OC

InChI Key: InChIKey=YVTMYRDTNPZNJO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase subunit beta (β-RNAP) (Escherichia coli)	BDBM50155487 (CHEMBL185900 | {(E)-5-[4-Hydroxy-5-((2E,4E)-2-meth...) Show SMILES CCCCC=CC=C(C)C(=O)c1c(O)cc(oc1=O)C(C)CCCC=NC(=O)OC |w:25.26,6.5,4.3| Show InChI InChI=1S/C23H31NO6/c1-5-6-7-8-9-13-17(3)21(26)20-18(25)15-19(30-22(20)27)16(2)12-10-11-14-24-23(28)29-4/h8-9,13-16,25H,5-7,10-12H2,1-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli				Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD
					More data for this Ligand-Target Pair