BDBM50155489 CHEMBL185050::{(E)-5-[5-((2E,4E)-2,5-Dimethyl-nona-2,4-dienoyl)-4-methoxy-6-oxo-6H-pyran-2-yl]-hex-1-enyl}-carbamic acid methyl ester

SMILES: CCCCC(C)=CC=C(C)C(=O)c1c(OC)cc(oc1=O)C(C)CCCC=NC(=O)OC

InChI Key: InChIKey=GBFKUMZWGJWJKO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase subunit beta (β-RNAP) (Escherichia coli)	BDBM50155489 (CHEMBL185050 | {(E)-5-[5-((2E,4E)-2,5-Dimethyl-non...) Show SMILES CCCCC(C)=CC=C(C)C(=O)c1c(OC)cc(oc1=O)C(C)CCCC=NC(=O)OC |w:27.28,7.6,4.4| Show InChI InChI=1S/C25H35NO6/c1-7-8-11-17(2)13-14-19(4)23(27)22-21(30-5)16-20(32-24(22)28)18(3)12-9-10-15-26-25(29)31-6/h13-16,18H,7-12H2,1-6H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli				Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD
					More data for this Ligand-Target Pair