BDBM50156338 CHEMBL3782016

SMILES: CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2cnc3ccccc3c2)n1

InChI Key: InChIKey=GCJHXHBCNCJIPK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156338 (CHEMBL3782016) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2cnc3ccccc3c2)n1 Show InChI InChI=1S/C22H21N7/c1-23-21-26-13-17(20(29-21)10-14-6-7-14)19-8-9-24-22(28-19)27-16-11-15-4-2-3-5-18(15)25-12-16/h2-5,8-9,11-14H,6-7,10H2,1H3,(H,23,26,29)(H,24,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair