BDBM50156374 CHEMBL3792428

SMILES: Nc1cc(ccn1)-c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1F

InChI Key: InChIKey=NOIUQKMOVSFHCW-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50156374 (CHEMBL3792428) Show SMILES Nc1cc(ccn1)-c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1F Show InChI InChI=1S/C22H17FN6O/c23-16-4-2-1-3-15(16)18-6-5-17(24)21(28-18)22(30)29-19-12-26-9-8-14(19)13-7-10-27-20(25)11-13/h1-12H,24H2,(H2,25,27)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Pim1 (unknown origin) using BAD peptide preincubated for 15 mins followed by ATP addition measured after 60 to 100 mins by Kinase-Glo r...				Bioorg Med Chem Lett 26: 2328-32 (2016) BindingDB Entry DOI: 10.7270/Q2WD42F0
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50156374 (CHEMBL3792428) Show SMILES Nc1cc(ccn1)-c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1F Show InChI InChI=1S/C22H17FN6O/c23-16-4-2-1-3-15(16)18-6-5-17(24)21(28-18)22(30)29-19-12-26-9-8-14(19)13-7-10-27-20(25)11-13/h1-12H,24H2,(H2,25,27)(H,29,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Pim3 (unknown origin) using BAD peptide preincubated for 15 mins followed by ATP addition measured after 60 to 100 mins by Kinase-Glo r...				Bioorg Med Chem Lett 26: 2328-32 (2016) BindingDB Entry DOI: 10.7270/Q2WD42F0
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50156374 (CHEMBL3792428) Show SMILES Nc1cc(ccn1)-c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1F Show InChI InChI=1S/C22H17FN6O/c23-16-4-2-1-3-15(16)18-6-5-17(24)21(28-18)22(30)29-19-12-26-9-8-14(19)13-7-10-27-20(25)11-13/h1-12H,24H2,(H2,25,27)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Pim2 (unknown origin) using BAD peptide preincubated for 15 mins followed by ATP addition measured after 60 to 100 mins by Kinase-Glo r...				Bioorg Med Chem Lett 26: 2328-32 (2016) BindingDB Entry DOI: 10.7270/Q2WD42F0
					More data for this Ligand-Target Pair