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BDBM50156426 (R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-[4-(5-m-tolyl-[1,2,4]oxadiazol-3-ylmethyl)-piperazin-1-yl]-propan-2-ol::CHEMBL186653

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4cccc(C)c4)CC3)ccc2s1

InChI Key: InChIKey=AACWQDWRPLXNNU-HXUWFJFHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156426   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50156426
PNG
((R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-[4-(5-m-to...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4cccc(C)c4)CC3)ccc2s1
Show InChI InChI=1S/C25H29N5O3S/c1-17-4-3-5-19(12-17)25-27-24(28-33-25)15-30-10-8-29(9-11-30)14-20(31)16-32-21-6-7-23-22(13-21)26-18(2)34-23/h3-7,12-13,20,31H,8-11,14-16H2,1-2H3/t20-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



CV Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria


Bioorg Med Chem Lett 14: 6017-21 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.077
More data for this
Ligand-Target Pair