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SMILES: O=C(N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1)c1ccncc1

InChI Key: InChIKey=NULLMYNWZQLJGN-HXUWFJFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156481   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50156481
PNG
((S)-4-Phenyl-1-[1-(pyridine-4-carbonyl)-2,3-dihydr...)
Show SMILES O=C(N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1)c1ccncc1
Show InChI InChI=1S/C23H20N4O4S/c28-22(17-8-11-24-12-9-17)26-13-10-18-14-19(6-7-21(18)26)32(30,31)27-15-20(25-23(27)29)16-4-2-1-3-5-16/h1-9,11-12,14,20H,10,13,15H2,(H,25,29)/t20-/m1/s1
UniProtKB/SwissProt

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PC sid
UniChem

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Article
PubMed
n/an/a 1.03E+4n/an/an/an/an/an/a



LG Life Sciences, Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of tubulin polymerisation

Bioorg Med Chem Lett 14: 6075-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.069
BindingDB Entry DOI: 10.7270/Q269731X
More data for this
Ligand-Target Pair