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SMILES: CN1CCN(CCOC(=O)N2CCc3cc(ccc23)S(=O)(=O)N2C[C@@H](NC2=O)c2ccccc2)CC1

InChI Key: InChIKey=ZSOGWUXBQKMIIU-JOCHJYFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156486   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50156486
PNG
(5-((S)-2-Oxo-4-phenyl-imidazolidine-1-sulfonyl)-2,...)
Show SMILES CN1CCN(CCOC(=O)N2CCc3cc(ccc23)S(=O)(=O)N2C[C@@H](NC2=O)c2ccccc2)CC1
Show InChI InChI=1S/C25H31N5O5S/c1-27-11-13-28(14-12-27)15-16-35-25(32)29-10-9-20-17-21(7-8-23(20)29)36(33,34)30-18-22(26-24(30)31)19-5-3-2-4-6-19/h2-8,17,22H,9-16,18H2,1H3,(H,26,31)/t22-/m1/s1
UniProtKB/SwissProt

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Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



LG Life Sciences, Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of tubulin polymerisation

Bioorg Med Chem Lett 14: 6075-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.069
BindingDB Entry DOI: 10.7270/Q269731X
More data for this
Ligand-Target Pair