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SMILES: CCOC(=O)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1

InChI Key: InChIKey=WXLTWGDLYGVLTO-QGZVFWFLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156489   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50156489
PNG
(5-((S)-2-Oxo-4-phenyl-imidazolidine-1-sulfonyl)-2,...)
Show SMILES CCOC(=O)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1
Show InChI InChI=1S/C20H21N3O5S/c1-2-28-20(25)22-11-10-15-12-16(8-9-18(15)22)29(26,27)23-13-17(21-19(23)24)14-6-4-3-5-7-14/h3-9,12,17H,2,10-11,13H2,1H3,(H,21,24)/t17-/m1/s1
UniProtKB/SwissProt

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PC sid
UniChem

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Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



LG Life Sciences, Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of tubulin polymerisation

Bioorg Med Chem Lett 14: 6075-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.069
BindingDB Entry DOI: 10.7270/Q269731X
More data for this
Ligand-Target Pair