BDBM50156490 (S)-1-[1-(4-Amino-benzoyl)-2,3-dihydro-1H-indole-5-sulfonyl]-4-phenyl-imidazolidin-2-one::CHEMBL186524

SMILES: Nc1ccc(cc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1

InChI Key: InChIKey=YZBUIQWOLSBWEX-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain [1-43] (Leishmania donovani)	BDBM50156490 ((S)-1-[1-(4-Amino-benzoyl)-2,3-dihydro-1H-indole-5...) Show SMILES Nc1ccc(cc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C24H22N4O4S/c25-19-8-6-17(7-9-19)23(29)27-13-12-18-14-20(10-11-22(18)27)33(31,32)28-15-21(26-24(28)30)16-4-2-1-3-5-16/h1-11,14,21H,12-13,15,25H2,(H,26,30)/t21-/m1/s1	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Compound was tested for inhibition of tubulin polymerisation				Bioorg Med Chem Lett 14: 6075-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.069 BindingDB Entry DOI: 10.7270/Q269731X
					More data for this Ligand-Target Pair