BDBM50156620 (+/-)-2-furan-2-yl-5-(octahydro-pyrido[1,2-a]pyrazin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl-amine::CHEMBL375846

SMILES: Nc1cc(nc2nc(nn12)-c1ccco1)N1CCN2CCCCC2C1

InChI Key: InChIKey=LNDBFNCGBUWYHT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50156620 ((+/-)-2-furan-2-yl-5-(octahydro-pyrido[1,2-a]pyraz...) Show SMILES Nc1cc(nc2nc(nn12)-c1ccco1)N1CCN2CCCCC2C1 Show InChI InChI=1S/C17H21N7O/c18-14-10-15(23-8-7-22-6-2-1-4-12(22)11-23)19-17-20-16(21-24(14)17)13-5-3-9-25-13/h3,5,9-10,12H,1-2,4,6-8,11,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane				J Med Chem 47: 6218-29 (2004) Article DOI: 10.1021/jm0494321 BindingDB Entry DOI: 10.7270/Q20V8DM9
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50156620 ((+/-)-2-furan-2-yl-5-(octahydro-pyrido[1,2-a]pyraz...) Show SMILES Nc1cc(nc2nc(nn12)-c1ccco1)N1CCN2CCCCC2C1 Show InChI InChI=1S/C17H21N7O/c18-14-10-15(23-8-7-22-6-2-1-4-12(22)11-23)19-17-20-16(21-24(14)17)13-5-3-9-25-13/h3,5,9-10,12H,1-2,4,6-8,11,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane				J Med Chem 47: 6218-29 (2004) Article DOI: 10.1021/jm0494321 BindingDB Entry DOI: 10.7270/Q20V8DM9
					More data for this Ligand-Target Pair