BDBM50156637 (7RS,9aSR)-N5-[2-(5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazol-4-ylmethyl)octahydropyrido[1,2-a]pyrazin-7-ylmethyl]-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine::CHEMBL223035
SMILES: Nc1nc(NC[C@H]2CC[C@@H]3CN(CCN3C2)c2ncccn2)nc2nc(nn12)-c1ccco1
InChI Key: InChIKey=BBVRFFOGAIOFTE-HUUCEWRRSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat)) | BDBM50156637 ((7RS,9aSR)-N5-[2-(5-chloro-1-methyl-3-trifluoromet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane | J Med Chem 47: 6218-29 (2004) Article DOI: 10.1021/jm0494321 BindingDB Entry DOI: 10.7270/Q20V8DM9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50156637 ((7RS,9aSR)-N5-[2-(5-chloro-1-methyl-3-trifluoromet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane | J Med Chem 47: 6218-29 (2004) Article DOI: 10.1021/jm0494321 BindingDB Entry DOI: 10.7270/Q20V8DM9 | |||||||||||
More data for this Ligand-Target Pair |