BDBM50156847 CHEMBL222051::N-{4-[5-(4-fluorophenyl)-2-(4-methylsulfinylbenzylsulfanyl)-3-(2-methylsulfanylethyl)-3H-imidazol-4-yl]pyridin-2-yl}acetamide

SMILES: CSCCn1c(SCc2ccc(cc2)S(C)=O)nc(c1-c1ccnc(NC(C)=O)c1)-c1ccc(F)cc1

InChI Key: InChIKey=FGGUYDBFEBTVNE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50156847 (CHEMBL222051 | N-{4-[5-(4-fluorophenyl)-2-(4-methy...) Show SMILES CSCCn1c(SCc2ccc(cc2)S(C)=O)nc(c1-c1ccnc(NC(C)=O)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H27FN4O2S3/c1-18(33)30-24-16-21(12-13-29-24)26-25(20-6-8-22(28)9-7-20)31-27(32(26)14-15-35-2)36-17-19-4-10-23(11-5-19)37(3)34/h4-13,16H,14-15,17H2,1-3H3,(H,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tübingen Curated by ChEMBL					Assay Description Inhibition of mitogen-activated protein kinase p38 alpha				J Med Chem 47: 6311-25 (2004) Article DOI: 10.1021/jm0496584 BindingDB Entry DOI: 10.7270/Q2N8799P
					More data for this Ligand-Target Pair