BDBM50157239 2''-Cyano-5''-[(4-cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-biphenyl-2-carboxylic acid::CHEMBL183548

SMILES: Cn1cncc1C(OCc1ccc(cc1)C#N)c1ccc(C#N)c(c1)-c1ccccc1C(O)=O

InChI Key: InChIKey=QFDVATDDSQALHP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase beta/geranylgeranyltransferase type I alpha subunit (Mus musculus)	BDBM50157239 (2''-Cyano-5''-[(4-cyano-benzyloxy)-(3-methyl-3H-im...) Show SMILES Cn1cncc1C(OCc1ccc(cc1)C#N)c1ccc(C#N)c(c1)-c1ccccc1C(O)=O Show InChI InChI=1S/C27H20N4O3/c1-31-17-30-15-25(31)26(34-16-19-8-6-18(13-28)7-9-19)20-10-11-21(14-29)24(12-20)22-4-2-3-5-23(22)27(32)33/h2-12,15,17,26H,16H2,1H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effective concentration against H-ras processing in transformed NIH3T3 cells				Bioorg Med Chem Lett 15: 153-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.014 BindingDB Entry DOI: 10.7270/Q2TT4QFC
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50157239 (2''-Cyano-5''-[(4-cyano-benzyloxy)-(3-methyl-3H-im...) Show SMILES Cn1cncc1C(OCc1ccc(cc1)C#N)c1ccc(C#N)c(c1)-c1ccccc1C(O)=O Show InChI InChI=1S/C27H20N4O3/c1-31-17-30-15-25(31)26(34-16-19-8-6-18(13-28)7-9-19)20-10-11-21(14-29)24(12-20)22-4-2-3-5-23(22)27(32)33/h2-12,15,17,26H,16H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bovine farnesyl transeferase				Bioorg Med Chem Lett 15: 153-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.014 BindingDB Entry DOI: 10.7270/Q2TT4QFC
					More data for this Ligand-Target Pair