BDBM50157544 2-(1H-benzimidazol-5-yl)-7,8-dimethoxy-4H-chromen-4-one::CHEMBL222547

SMILES: COc1ccc2c(oc(cc2=O)-c2ccc3nc[nH]c3c2)c1OC

InChI Key: InChIKey=KGFBTYNMXJZNQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50157544 (2-(1H-benzimidazol-5-yl)-7,8-dimethoxy-4H-chromen-...) Show SMILES COc1ccc2c(oc(cc2=O)-c2ccc3nc[nH]c3c2)c1OC Show InChI InChI=1S/C18H14N2O4/c1-22-15-6-4-11-14(21)8-16(24-17(11)18(15)23-2)10-3-5-12-13(7-10)20-9-19-12/h3-9H,1-2H3,(H,19,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
BU-Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assay				J Med Chem 47: 6466-75 (2004) Article DOI: 10.1021/jm040810b BindingDB Entry DOI: 10.7270/Q2P55N1R
					More data for this Ligand-Target Pair