BDBM50157757 CHEMBL221991::N1-((5-((3-oxo-5,6-dihydroimidazo[2,1-b]thiazol-2(3H)-ylidene)methyl)furan-2-yl)methyl)-N2-phenyloxalamide

SMILES: O=C(NCc1ccc(\C=c2\sc3=NCCn3c2=O)o1)C(=O)Nc1ccccc1

InChI Key: InChIKey=IIMCLZRVLAPXDI-XNTDXEJSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteine protease falcipain-3 (Plasmodium falciparum)	BDBM50157757 (CHEMBL221991 | N1-((5-((3-oxo-5,6-dihydroimidazo[2...) Show SMILES O=C(NCc1ccc(\C=c2\sc3=NCCn3c2=O)o1)C(=O)Nc1ccccc1 |t:11| Show InChI InChI=1S/C19H16N4O4S/c24-16(17(25)22-12-4-2-1-3-5-12)21-11-14-7-6-13(27-14)10-15-18(26)23-9-8-20-19(23)28-15/h1-7,10H,8-9,11H2,(H,21,24)(H,22,25)/b15-10+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-3				J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D
					More data for this Ligand-Target Pair
Falcipain-2 (Plasmodium falciparum)	BDBM50157757 (CHEMBL221991 | N1-((5-((3-oxo-5,6-dihydroimidazo[2...) Show SMILES O=C(NCc1ccc(\C=c2\sc3=NCCn3c2=O)o1)C(=O)Nc1ccccc1 |t:11| Show InChI InChI=1S/C19H16N4O4S/c24-16(17(25)22-12-4-2-1-3-5-12)21-11-14-7-6-13(27-14)10-15-18(26)23-9-8-20-19(23)28-15/h1-7,10H,8-9,11H2,(H,21,24)(H,22,25)/b15-10+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-2				J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D
					More data for this Ligand-Target Pair