BDBM50157836 7-Benzyl-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-dione::CHEMBL183133
SMILES: On1c(=O)[nH]c2c(Cc3ccccc3)coc2c1=O
InChI Key: InChIKey=ZTYGZYOHPCUUJF-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA excision repair protein ERCC-5 (Homo sapiens (Human)) | BDBM50157836 (7-Benzyl-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 0.0610 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against the xeroderma pigmentosum G | Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Flap endonuclease 1 (Homo sapiens (Human)) | BDBM50157836 (7-Benzyl-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-di...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 0.0380 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against the Flap endonuclease-1 | Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46 | |||||||||||
More data for this Ligand-Target Pair |