BDBM50157838 3-Hydroxy-7-(4-methoxy-phenyl)-1H-furo[3,2-d]pyrimidine-2,4-dione::CHEMBL359747

SMILES: COc1ccc(cc1)-c1coc2c1[nH]c(=O)n(O)c2=O

InChI Key: InChIKey=QZASXVAFBAMIJS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50157838 (3-Hydroxy-7-(4-methoxy-phenyl)-1H-furo[3,2-d]pyrim...) Show SMILES COc1ccc(cc1)-c1coc2c1[nH]c(=O)n(O)c2=O Show InChI InChI=1S/C13H10N2O5/c1-19-8-4-2-7(3-5-8)9-6-20-11-10(9)14-13(17)15(18)12(11)16/h2-6,18H,1H3,(H,14,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0340	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the Flap endonuclease-1				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50157838 (3-Hydroxy-7-(4-methoxy-phenyl)-1H-furo[3,2-d]pyrim...) Show SMILES COc1ccc(cc1)-c1coc2c1[nH]c(=O)n(O)c2=O Show InChI InChI=1S/C13H10N2O5/c1-19-8-4-2-7(3-5-8)9-6-20-11-10(9)14-13(17)15(18)12(11)16/h2-6,18H,1H3,(H,14,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the xeroderma pigmentosum G				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair