BDBM50157845 7-(4-Bromo-phenyl)-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-dione::CHEMBL180566

SMILES: On1c(=O)[nH]c2c(coc2c1=O)-c1ccc(Br)cc1

InChI Key: InChIKey=HRJWRXZQYNJFKL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50157845 (7-(4-Bromo-phenyl)-3-hydroxy-1H-furo[3,2-d]pyrimid...) Show SMILES On1c(=O)[nH]c2c(coc2c1=O)-c1ccc(Br)cc1 Show InChI InChI=1S/C12H7BrN2O4/c13-7-3-1-6(2-4-7)8-5-19-10-9(8)14-12(17)15(18)11(10)16/h1-5,18H,(H,14,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the Flap endonuclease-1				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50157845 (7-(4-Bromo-phenyl)-3-hydroxy-1H-furo[3,2-d]pyrimid...) Show SMILES On1c(=O)[nH]c2c(coc2c1=O)-c1ccc(Br)cc1 Show InChI InChI=1S/C12H7BrN2O4/c13-7-3-1-6(2-4-7)8-5-19-10-9(8)14-12(17)15(18)11(10)16/h1-5,18H,(H,14,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.327	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the xeroderma pigmentosum G				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair