BDBM50157920 2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluoromethoxy-1H-indol-3-ylmethyl]-phenoxy}-2-methyl-propionic acid::CHEMBL181554

SMILES: COc1ccc(cc1)C(=O)n1c(C)c(Cc2cccc(OC(C)(C)C(O)=O)c2)c2cc(OC(F)(F)F)ccc12

InChI Key: InChIKey=WTIUDROYDYCRCV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50157920 (2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluorome...) Show SMILES COc1ccc(cc1)C(=O)n1c(C)c(Cc2cccc(OC(C)(C)C(O)=O)c2)c2cc(OC(F)(F)F)ccc12 Show InChI InChI=1S/C29H26F3NO6/c1-17-23(15-18-6-5-7-21(14-18)38-28(2,3)27(35)36)24-16-22(39-29(30,31)32)12-13-25(24)33(17)26(34)19-8-10-20(37-4)11-9-19/h5-14,16H,15H2,1-4H3,(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of human Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 15: 357-62 (2004) Article DOI: 10.1016/j.bmcl.2004.10.068 BindingDB Entry DOI: 10.7270/Q27W6BNP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50157920 (2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluorome...) Show SMILES COc1ccc(cc1)C(=O)n1c(C)c(Cc2cccc(OC(C)(C)C(O)=O)c2)c2cc(OC(F)(F)F)ccc12 Show InChI InChI=1S/C29H26F3NO6/c1-17-23(15-18-6-5-7-21(14-18)38-28(2,3)27(35)36)24-16-22(39-29(30,31)32)12-13-25(24)33(17)26(34)19-8-10-20(37-4)11-9-19/h5-14,16H,15H2,1-4H3,(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of human Peroxisome proliferator activated receptor delta				Bioorg Med Chem Lett 15: 357-62 (2004) Article DOI: 10.1016/j.bmcl.2004.10.068 BindingDB Entry DOI: 10.7270/Q27W6BNP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50157920 (2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluorome...) Show SMILES COc1ccc(cc1)C(=O)n1c(C)c(Cc2cccc(OC(C)(C)C(O)=O)c2)c2cc(OC(F)(F)F)ccc12 Show InChI InChI=1S/C29H26F3NO6/c1-17-23(15-18-6-5-7-21(14-18)38-28(2,3)27(35)36)24-16-22(39-29(30,31)32)12-13-25(24)33(17)26(34)19-8-10-20(37-4)11-9-19/h5-14,16H,15H2,1-4H3,(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of human Peroxisome proliferator activated receptor gamma				Bioorg Med Chem Lett 15: 357-62 (2004) Article DOI: 10.1016/j.bmcl.2004.10.068 BindingDB Entry DOI: 10.7270/Q27W6BNP
					More data for this Ligand-Target Pair