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SMILES: CCCS(=O)(=O)NC1C2CCC1Cc1ccccc1C2

InChI Key: InChIKey=RXNKZDVMZSFLFU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157986   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2


(Homo sapiens (Human))		BDBM50157986
PNG
(CHEMBL360239 | Propane-1-sulfonic acid tricyclo[8....)
Show SMILES CCCS(=O)(=O)NC1C2CCC1Cc1ccccc1C2 |THB:6:7:19.12.13.18:9.10,14:13:7:9.10,17:18:7:9.10|
Show InChI InChI=1S/C16H23NO2S/c1-2-9-20(18,19)17-16-14-7-8-15(16)11-13-6-4-3-5-12(13)10-14/h3-6,14-17H,2,7-11H2,1H3
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Similars
Article
PubMed
n/an/a 721n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cells

Bioorg Med Chem Lett 15: 373-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.062
BindingDB Entry DOI: 10.7270/Q2445KZQ
More data for this
Ligand-Target Pair