BDBM50158277 5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl-(2-hydroxy-2-methyl-propyl)-carbamoyl]-methyl}-amide::CHEMBL361555

SMILES: CC(C)(O)CN(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=LZVJXRVRIMWUDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50158277 (5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl...) Show SMILES CC(C)(O)CN(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C20H26ClN3O3/c1-20(2,27)12-24(15-5-3-4-6-15)18(25)11-22-19(26)17-10-13-9-14(21)7-8-16(13)23-17/h7-10,15,23,27H,3-6,11-12H2,1-2H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against glycogen phosphorylase				Bioorg Med Chem Lett 15: 459-65 (2004) Article DOI: 10.1016/j.bmcl.2004.10.048 BindingDB Entry DOI: 10.7270/Q26W99K6
					More data for this Ligand-Target Pair