BDBM50158436 CHEMBL224624::N-[3-(4-methoxyphenoxy)-4-pyridinyl]methanesulfonamide

SMILES: COc1ccc(Oc2cnccc2NS(C)(=O)=O)cc1

InChI Key: InChIKey=SJQYXSIKYYHNSV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50158436 (CHEMBL224624 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...) Show SMILES COc1ccc(Oc2cnccc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H14N2O4S/c1-18-10-3-5-11(6-4-10)19-13-9-14-8-7-12(13)15-20(2,16)17/h3-9H,1-2H3,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Liège Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production				J Med Chem 47: 6749-59 (2004) Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50158436 (CHEMBL224624 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...) Show SMILES COc1ccc(Oc2cnccc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H14N2O4S/c1-18-10-3-5-11(6-4-10)19-13-9-14-8-7-12(13)15-20(2,16)17/h3-9H,1-2H3,(H,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Liège Curated by ChEMBL					Assay Description Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...				J Med Chem 47: 6749-59 (2004) Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK
					More data for this Ligand-Target Pair