BDBM50158608 (4-Chloro-3-methyl-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-methanone::CHEMBL179372

SMILES: C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(Cl)c(C)c1

InChI Key: InChIKey=PWRBPHUOIIYBHI-MRXNPFEDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50158608 ((4-Chloro-3-methyl-phenyl)-{2-[2-((R)-2-methyl-pyr...) Show SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C23H24ClNO2/c1-15-12-17(5-7-21(15)24)23(26)18-6-8-22-19(13-18)14-20(27-22)9-11-25-10-3-4-16(25)2/h5-8,12-14,16H,3-4,9-11H2,1-2H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor				J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50158608 ((4-Chloro-3-methyl-phenyl)-{2-[2-((R)-2-methyl-pyr...) Show SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(Cl)c(C)c1 Show InChI InChI=1S/C23H24ClNO2/c1-15-12-17(5-7-21(15)24)23(26)18-6-8-22-19(13-18)14-20(27-22)9-11-25-10-3-4-16(25)2/h5-8,12-14,16H,3-4,9-11H2,1-2H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing rat histamine H3 receptor				J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST
					More data for this Ligand-Target Pair