BDBM50158752 2-{5-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-N-(2-hydroxy-5-nitro-phenyl)-acetamide::CHEMBL176083

SMILES: Oc1ccc(cc1NC(=O)CN1C(=S)S\C(=C/c2ccccc2Cl)C1=O)[N+]([O-])=O

InChI Key: InChIKey=LARGCCICCRRFQG-CHHVJCJISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158752 (2-{5-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-4-oxo-...) Show SMILES Oc1ccc(cc1NC(=O)CN1C(=S)S\C(=C/c2ccccc2Cl)C1=O)[N+]([O-])=O Show InChI InChI=1S/C18H12ClN3O5S2/c19-12-4-2-1-3-10(12)7-15-17(25)21(18(28)29-15)9-16(24)20-13-8-11(22(26)27)5-6-14(13)23/h1-8,23H,9H2,(H,20,24)/b15-7-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158752 (2-{5-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-4-oxo-...) Show SMILES Oc1ccc(cc1NC(=O)CN1C(=S)S\C(=C/c2ccccc2Cl)C1=O)[N+]([O-])=O Show InChI InChI=1S/C18H12ClN3O5S2/c19-12-4-2-1-3-10(12)7-15-17(25)21(18(28)29-15)9-16(24)20-13-8-11(22(26)27)5-6-14(13)23/h1-8,23H,9H2,(H,20,24)/b15-7-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair