BDBM50159112 2-(4-Cyclopropyl-piperazin-1-yl)-6-trifluoromethyl-quinoline::CHEMBL179629

SMILES: FC(F)(F)c1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1

InChI Key: InChIKey=MHWHBMVPYRSQGR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159112 (2-(4-Cyclopropyl-piperazin-1-yl)-6-trifluoromethyl...) Show SMILES FC(F)(F)c1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C17H18F3N3/c18-17(19,20)13-2-5-15-12(11-13)1-6-16(21-15)23-9-7-22(8-10-23)14-3-4-14/h1-2,5-6,11,14H,3-4,7-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair