BDBM50159323 3,5-Dichloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin-1-yl-ethoxy)-phenyl]-4,5-dihydro-1H-imidazol-4-yl}-phenol::CHEMBL365779

SMILES: Oc1cc(Cl)c([C@@H]2N=CN[C@@H]2c2ccc(OCCN3CCCCC3)cc2Cl)c(Cl)c1

InChI Key: InChIKey=IOMUFHNCTKDSQD-YADHBBJMSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50159323 (3,5-Dichloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin...) Show SMILES Oc1cc(Cl)c([C@@H]2N=CN[C@@H]2c2ccc(OCCN3CCCCC3)cc2Cl)c(Cl)c1 |c:7| Show InChI InChI=1S/C22H24Cl3N3O2/c23-17-12-15(30-9-8-28-6-2-1-3-7-28)4-5-16(17)21-22(27-13-26-21)20-18(24)10-14(29)11-19(20)25/h4-5,10-13,21-22,29H,1-3,6-9H2,(H,26,27)/t21-,22+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Effective concentration against estrogen receptor alpha of MCF-7-2a cells				J Med Chem 48: 466-74 (2005) Article DOI: 10.1021/jm040855c BindingDB Entry DOI: 10.7270/Q20864T2
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50159323 (3,5-Dichloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin...) Show SMILES Oc1cc(Cl)c([C@@H]2N=CN[C@@H]2c2ccc(OCCN3CCCCC3)cc2Cl)c(Cl)c1 |c:7| Show InChI InChI=1S/C22H24Cl3N3O2/c23-17-12-15(30-9-8-28-6-2-1-3-7-28)4-5-16(17)21-22(27-13-26-21)20-18(24)10-14(29)11-19(20)25/h4-5,10-13,21-22,29H,1-3,6-9H2,(H,26,27)/t21-,22+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Effective concentration against estrogen receptor beta of MCF-7-2a cells				J Med Chem 48: 466-74 (2005) Article DOI: 10.1021/jm040855c BindingDB Entry DOI: 10.7270/Q20864T2
					More data for this Ligand-Target Pair