BDBM50159324 3-Chloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin-1-yl-ethoxy)-phenyl]-4,5-dihydro-1H-imidazol-4-yl}-phenol::CHEMBL192432

SMILES: Oc1ccc([C@@H]2N=CN[C@@H]2c2ccc(OCCN3CCCCC3)cc2Cl)c(Cl)c1

InChI Key: InChIKey=JLVDPPIAEWJQPN-FCHUYYIVSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50159324 (3-Chloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin-1-y...) Show SMILES Oc1ccc([C@@H]2N=CN[C@@H]2c2ccc(OCCN3CCCCC3)cc2Cl)c(Cl)c1 |c:6| Show InChI InChI=1S/C22H25Cl2N3O2/c23-19-12-15(28)4-6-17(19)21-22(26-14-25-21)18-7-5-16(13-20(18)24)29-11-10-27-8-2-1-3-9-27/h4-7,12-14,21-22,28H,1-3,8-11H2,(H,25,26)/t21-,22+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Effective concentration against estrogen receptor alpha of MCF-7-2a cells				J Med Chem 48: 466-74 (2005) Article DOI: 10.1021/jm040855c BindingDB Entry DOI: 10.7270/Q20864T2
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50159324 (3-Chloro-4-{(4S,5R)-5-[2-chloro-4-(2-piperidin-1-y...) Show SMILES Oc1ccc([C@@H]2N=CN[C@@H]2c2ccc(OCCN3CCCCC3)cc2Cl)c(Cl)c1 |c:6| Show InChI InChI=1S/C22H25Cl2N3O2/c23-19-12-15(28)4-6-17(19)21-22(26-14-25-21)18-7-5-16(13-20(18)24)29-11-10-27-8-2-1-3-9-27/h4-7,12-14,21-22,28H,1-3,8-11H2,(H,25,26)/t21-,22+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Effective concentration against estrogen receptor beta of MCF-7-2a cells				J Med Chem 48: 466-74 (2005) Article DOI: 10.1021/jm040855c BindingDB Entry DOI: 10.7270/Q20864T2
					More data for this Ligand-Target Pair