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BDBM50159558 CHEMBL3786009

SMILES: COc1c(NC(=O)C(=O)c2ccc(OCCN(CC(O)=O)CC(O)=O)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key: InChIKey=KPKQLGCKIABZDW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159558   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Homo sapiens (Human))		BDBM50159558
PNG
(CHEMBL3786009)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN(CC(O)=O)CC(O)=O)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1S/C30H35N3O10S/c1-30(2,3)18-14-22(28(42-4)23(15-18)32-44(5,40)41)31-29(39)27(38)21-10-11-24(20-9-7-6-8-19(20)21)43-13-12-33(16-25(34)35)17-26(36)37/h6-11,14-15,32H,12-13,16-17H2,1-5H3,(H,31,39)(H,34,35)(H,36,37)
KEGG

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a<3.16E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...

Bioorg Med Chem Lett 26: 1901-4 (2016)


BindingDB Entry DOI: 10.7270/Q22R3TJ2
More data for this
Ligand-Target Pair