BDBM50159568 1-Methyl-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-1H-indole::CHEMBL175504

SMILES: COc1cc(\C=C/c2ccc3n(C)ccc3c2)cc(OC)c1OC

InChI Key: InChIKey=LPAPKBFMHBYENM-WAYWQWQTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin (Bos taurus)	BDBM50159568 (1-Methyl-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...) Show SMILES COc1cc(\C=C/c2ccc3n(C)ccc3c2)cc(OC)c1OC Show InChI InChI=1S/C20H21NO3/c1-21-10-9-16-11-14(7-8-17(16)21)5-6-15-12-18(22-2)20(24-4)19(13-15)23-3/h5-13H,1-4H3/b6-5-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description In vitro inhibitory concentration value against bovine brain tubulin polymerization				J Med Chem 48: 556-68 (2005) Article DOI: 10.1021/jm0310737 BindingDB Entry DOI: 10.7270/Q2GB23JK
					More data for this Ligand-Target Pair