BDBM50159679 6-Methoxy-4-morpholin-4-yl-chromen-2-one::6-methoxy-4-morpholino-2H-chromen-2-one::CHEMBL175510

SMILES: COc1ccc2oc(=O)cc(N3CCOCC3)c2c1

InChI Key: InChIKey=UEDWCBYLFYRZFY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50159679 (6-Methoxy-4-morpholin-4-yl-chromen-2-one | 6-metho...) Show SMILES COc1ccc2oc(=O)cc(N3CCOCC3)c2c1 Show InChI InChI=1S/C14H15NO4/c1-17-10-2-3-13-11(8-10)12(9-14(16)19-13)15-4-6-18-7-5-15/h2-3,8-9H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University Curated by ChEMBL					Assay Description Inhibition of DNA dependent protein kinase isolated from HeLa cells				J Med Chem 48: 569-85 (2005) Article DOI: 10.1021/jm049526a BindingDB Entry DOI: 10.7270/Q2BK1BV9
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50159679 (6-Methoxy-4-morpholin-4-yl-chromen-2-one | 6-metho...) Show SMILES COc1ccc2oc(=O)cc(N3CCOCC3)c2c1 Show InChI InChI=1S/C14H15NO4/c1-17-10-2-3-13-11(8-10)12(9-14(16)19-13)15-4-6-18-7-5-15/h2-3,8-9H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Hradec Kralove Curated by ChEMBL					Assay Description Inhibition of DNA-PK (unknown origin)				J Med Chem 58: 41-71 (2015) Article DOI: 10.1021/jm501026z BindingDB Entry DOI: 10.7270/Q2P84DJ7
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50159679 (6-Methoxy-4-morpholin-4-yl-chromen-2-one | 6-metho...) Show SMILES COc1ccc2oc(=O)cc(N3CCOCC3)c2c1 Show InChI InChI=1S/C14H15NO4/c1-17-10-2-3-13-11(8-10)12(9-14(16)19-13)15-4-6-18-7-5-15/h2-3,8-9H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of DNA-dependent protein kinase				Bioorg Med Chem Lett 20: 3649-53 (2010) Article DOI: 10.1016/j.bmcl.2010.04.102 BindingDB Entry DOI: 10.7270/Q2R49QX1
					More data for this Ligand-Target Pair