BDBM50160107 2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-nicotinonitrile::CHEMBL361119

SMILES: Clc1ccc(cc1)-c1cc(C#N)c(OCc2ccccc2)nc1-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=QUAZWCZRNVNLQQ-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160107 (2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-ph...) Show SMILES Clc1ccc(cc1)-c1cc(C#N)c(OCc2ccccc2)nc1-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C25H15Cl3N2O/c26-19-8-6-17(7-9-19)22-12-18(14-29)25(31-15-16-4-2-1-3-5-16)30-24(22)21-11-10-20(27)13-23(21)28/h1-13H,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration tested against human Cannabinoid receptor 2 (hCB2)				Bioorg Med Chem Lett 15: 645-51 (2005) Article DOI: 10.1016/j.bmcl.2004.11.031 BindingDB Entry DOI: 10.7270/Q2X929SW
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160107 (2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-ph...) Show SMILES Clc1ccc(cc1)-c1cc(C#N)c(OCc2ccccc2)nc1-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C25H15Cl3N2O/c26-19-8-6-17(7-9-19)22-12-18(14-29)25(31-15-16-4-2-1-3-5-16)30-24(22)21-11-10-20(27)13-23(21)28/h1-13H,15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration against human Cannabinoid receptor 1 (hCB1)				Bioorg Med Chem Lett 15: 645-51 (2005) Article DOI: 10.1016/j.bmcl.2004.11.031 BindingDB Entry DOI: 10.7270/Q2X929SW
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160107 (2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-ph...) Show SMILES Clc1ccc(cc1)-c1cc(C#N)c(OCc2ccccc2)nc1-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C25H15Cl3N2O/c26-19-8-6-17(7-9-19)22-12-18(14-29)25(31-15-16-4-2-1-3-5-16)30-24(22)21-11-10-20(27)13-23(21)28/h1-13H,15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1)				Bioorg Med Chem Lett 15: 645-51 (2005) Article DOI: 10.1016/j.bmcl.2004.11.031 BindingDB Entry DOI: 10.7270/Q2X929SW
					More data for this Ligand-Target Pair