BDBM50160279 CHEMBL3787224

SMILES: COc1ccc(cc1)[C@@H]1[C@H](N(C2CCN(CC2)C(=O)n2cncn2)C1=O)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=VIFSKVIAVYCQIJ-DNQXCXABSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50160279 (CHEMBL3787224) Show SMILES COc1ccc(cc1)[C@@H]1[C@H](N(C2CCN(CC2)C(=O)n2cncn2)C1=O)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C26H29N5O5/c1-34-20-7-4-17(5-8-20)23-24(18-6-9-21(35-2)22(14-18)36-3)31(25(23)32)19-10-12-29(13-11-19)26(33)30-16-27-15-28-30/h4-9,14-16,19,23-24H,10-13H2,1-3H3/t23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...				J Med Chem 59: 2612-32 (2016) BindingDB Entry DOI: 10.7270/Q21R6SC7
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50160279 (CHEMBL3787224) Show SMILES COc1ccc(cc1)[C@@H]1[C@H](N(C2CCN(CC2)C(=O)n2cncn2)C1=O)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C26H29N5O5/c1-34-20-7-4-17(5-8-20)23-24(18-6-9-21(35-2)22(14-18)36-3)31(25(23)32)19-10-12-29(13-11-19)26(33)30-16-27-15-28-30/h4-9,14-16,19,23-24H,10-13H2,1-3H3/t23-,24-/m1/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	725	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain membranes using using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as reduction in [14C]ethanolamine produ...				J Med Chem 59: 2612-32 (2016) BindingDB Entry DOI: 10.7270/Q21R6SC7
					More data for this Ligand-Target Pair