BDBM50160398 CHEMBL3786130

SMILES: Clc1ccccc1C(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O

InChI Key: InChIKey=KTIVNJRFNBDBRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50160398 (CHEMBL3786130) Show SMILES Clc1ccccc1C(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O |c:11| Show InChI InChI=1S/C25H17ClN2O3/c26-20-12-6-5-11-18(20)24(29)28-22(16-8-2-1-3-9-16)15-21(27-28)19-14-17-10-4-7-13-23(17)31-25(19)30/h1-14,22H,15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Anhui Medical University Curated by ChEMBL					Assay Description Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay				Eur J Med Chem 112: 231-51 (2016) BindingDB Entry DOI: 10.7270/Q2SB47N4
					More data for this Ligand-Target Pair