BDBM50160449 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-fluoro-phenyl)-ethyl]-4,4-dimethyl-piperidin-3-ylmethyl}-urea::CHEMBL362179

SMILES: CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CCC2(C)C)cc(c1)-c1nnnn1C

InChI Key: InChIKey=JLDWJHQDXOHRRF-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50160449 (1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3...) Show SMILES CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CCC2(C)C)cc(c1)-c1nnnn1C Show InChI InChI=1S/C27H36FN7O/c1-5-19-14-21(25-31-32-33-34(25)4)16-24(15-19)30-26(36)29-17-22-18-35(13-11-27(22,2)3)12-10-20-6-8-23(28)9-7-20/h6-9,14-16,22H,5,10-13,17-18H2,1-4H3,(H2,29,30,36)/t22-/m0/s1	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for inhibition of human C-C chemokine receptor type 3 expressed in CHO cells				Bioorg Med Chem Lett 15: 787-91 (2005) Article DOI: 10.1016/j.bmcl.2004.11.006 BindingDB Entry DOI: 10.7270/Q2H41QXT
					More data for this Ligand-Target Pair