BDBM50160463 1-{(S)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL362490

SMILES: Cn1nnnc1-c1cccc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)cc3)C2)c1

InChI Key: InChIKey=VJZFYTPWAOAASO-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50160463 (1-{(S)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-y...) Show SMILES Cn1nnnc1-c1cccc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)cc3)C2)c1 Show InChI InChI=1S/C23H28FN7O/c1-30-22(27-28-29-30)19-5-2-6-21(14-19)26-23(32)25-15-18-4-3-12-31(16-18)13-11-17-7-9-20(24)10-8-17/h2,5-10,14,18H,3-4,11-13,15-16H2,1H3,(H2,25,26,32)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for inhibition of human C-C chemokine receptor type 3 expressed in CHO cells				Bioorg Med Chem Lett 15: 787-91 (2005) Article DOI: 10.1016/j.bmcl.2004.11.006 BindingDB Entry DOI: 10.7270/Q2H41QXT
					More data for this Ligand-Target Pair