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SMILES: Cc1cccc(n1)C#Cc1cccc(OC(=O)CCCc2ccccc2)c1

InChI Key: InChIKey=LNJBGOKLCBSIQI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160628   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50160628
PNG
(4-Phenyl-butyric acid 3-(6-methyl-pyridin-2-ylethy...)
Show SMILES Cc1cccc(n1)C#Cc1cccc(OC(=O)CCCc2ccccc2)c1
Show InChI InChI=1S/C24H21NO2/c1-19-8-5-13-22(25-19)17-16-21-12-6-14-23(18-21)27-24(26)15-7-11-20-9-3-2-4-10-20/h2-6,8-10,12-14,18H,7,11,15H2,1H3
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Article
PubMed
n/an/a 1.17E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay

Bioorg Med Chem Lett 15: 945-9 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.047
BindingDB Entry DOI: 10.7270/Q2QN6681
More data for this
Ligand-Target Pair